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Pharmaceutics

Dosage/Formulation Development

Solid Dosage Forms and Modified Drug Delivery Systems

SRI has experience and expertise in development of solid dosage forms and modified drug delivery systems for oral and other routes of administration. We have the capability for solid dose formulation by both dry and wet granulation methods along with direct compression using extrusion spheronization, high shear granulators, fluid bed granulation etc.

Tablets

• Orally disintegrating tablet
• Immediate release tablets
• Delayed release tablet
• Sustained release tablet
• Minitablets

Capsules (Hard Gelatin and HPMC Capsules)

• Liquid filled capsules
• Powder and bead filled capsules
• Minicapsules
• Enteric coating of Capsules

Multiparticulate Systems

• Extruded Beads / granules
• Microspheres
• Lyophilized powders

Minicapsules and Minitablets

If you need to test your formulation in animal models such as rats and guinea pigs before testing in bigger species SRI has a solution.

We have experience in development and manufacturing of Minitablets and Minicapsules and enteric coating them (if required) suitable for oral administration to ratsand higher species.

Tablets and Capsules Coating

SRI has capabilities for providing services for coating of capsules and tablets of all sizes ranging from bench to pilot scale.

We have experience for coating the following dosage forms for both functional and non functional coating

• Hard gelatin capsules

. Liquid filled capsules

. Bead/ powder filled

• Minicapsules
• Tablets
• Minitablets
• Multiparticulate

. Beads

. Granules

. Microspheres

We can accommodate batch sizes from one gram to kilograms for R & D batches to clinical supplies.

Our unique way of coating minicapsules and minitablets is a perfect solution for preparation of enteric coated dosage forms for in vivo studies especially designed for small animals such as rats and rodents.

Liquid Formulations

SRI’s Pharmaceutical Formulation Design group also specializes in development of liquid formulations such as:

• Emulsions
• Dispersions
• Syrups
• Solutions
  
  

If required we use our HTS Screening technology for selecting and incorporating the rightful excipients.

We use the traditional homogenizers for preparation of emulsions and suspensions and also state of the art Microfluidizer for the development and preparation of stable nano-dispersions, nano-emulsions, microencapsulation in polymers, Solids-in-liquid suspensions etc.

Semisolids

SRI has the experience and capability to develop and manufacture semi solid formulations such as the following.

• Gels
• Ointments
• Creams

Alternative Drug Delivery Systems

SRI also has expertise in development of alternative or specialized drug delivery systems. We have experience in developing formulations for the following delivery systems.

• Nasal formulations
• Vaginal formulations
• Polymeric films
• Extruded implants
• Transdermal delivery systems

Back to Pharmaceutical Formulation Design

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     Last Updated Mar 19, 2010